Endocrine Abstracts

Background: Many chemicals present within the environment, as well as natural and artificial components of our diet, have the potential to interfere with the physiological role of hormones, interfering with hormone biosynthesis, signalling or metabolism. In the last years AMH, a protein secreted by granulosa cells, has emerged as a reliable marker of ovarian reserve. It is largely accepted the influence of age and smoking on AMH serum levels, although a clear effect of environ...

Introduction: While searching for mechanisms contributing to the increased mortality of acromegaly, we have previously described an unexpected sympathoinhibition in newly diagnosed patients (Seravalle et al., Clin Endocrinol 77:262, 2012) and interpreted this finding as an adaptive phenomenon. It has also been shown that centrally administered somatostatin (SS) inhibits peripheral sympathetic outflow in rodents (Rettig et al., Am J Physiol 257:R588, 1989). Ba...